ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the degree or outcome of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterised by vasospasm and tissue ischemia has long been connected with coadministration of ritonavirErgotamine: Alpha-adrenergic blocking agent wit